Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Kdr  kinase insert domain protein receptor   (Synonyms: Flk1, Flk-1, orv, vascular endothelial growth factor receptor- 2, VEGFR2, VEGFR-2, VEGF receptor-2)
Results	Reference
1	J:53085 Adams RH, Wilkinson GA, Weiss C, Diella F, Gale NW, Deutsch U, Risau W, Klein R, Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis. Genes Dev. 1999 Feb 1;13(3):295-306
1*	J:69389 Ayadi A, Suelves M, Dolle P, Wasylyk B, Net, an Ets ternary complex transcription factor, is expressed in sites of vasculogenesis, angiogenesis, and chondrogenesis during mouse development. Mech Dev. 2001 Apr;102(1-2):205-8
1	J:32219 Carmeliet P, Ferreira V, Breier G, Pollefeyt S, Kieckens L, Gertsenstein M, Fahrig M, Vandenhoeck A, Harpal K, Eberhardt C, Declercq C, Pawling J, Moons L, Collen D, Risau W, Nagy A, Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature. 1996 Apr 4;380(6573):435-9
1*	J:41526 Ema M, Taya S, Yokotani N, Sogawa K, Matsuda Y, Fujii-Kuriyama Y, A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development. Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4273-8
1*	J:118798 Fan B, Brennan J, Grant D, Peale F, Rangell L, Kirchhofer D, Hepatocyte growth factor activator inhibitor-1 (HAI-1) is essential for the integrity of basement membranes in the developing placental labyrinth. Dev Biol. 2007 Mar 1;303(1):222-30
1	J:54197 Giroux S, Tremblay M, Bernard D, Cardin-Girard JF, Aubry S, Larouche L, Rousseau S, Huot J, Landry J, Jeannotte L, Charron J, Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta. Curr Biol. 1999 Apr 8;9(7):369-72
1	J:113422 Harrelson Z, Papaioannou VE, Segmental expression of the T-box transcription factor, Tbx2, during early somitogenesis. Dev Dyn. 2006 Nov;235(11):3080-4
1	J:55926 Isobe T, Yoshino M, Lindahal KF, Mizuno K, Koide T, Moriwaki K, Shiroishi T, F. Genetic Strains Research Center. Analysis of the genetic structure of Pb hotspot in the Class II of MHC. Natl Inst Genet Jpn Annual Report. 1997;48:87-101
1	J:215739 Kazanskaya O, Ohkawara B, Heroult M, Wu W, Maltry N, Augustin HG, Niehrs C, The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development. Development. 2008 Nov;135(22):3655-64
1	J:62571 Krebs LT, Xue Y, Norton CR, Shutter JR, Maguire M, Sundberg JP, Gallahan D, Closson V, Kitajewski J, Callahan R, Smith GH, Stark KL, Gridley T, Notch signaling is essential for vascular morphogenesis in mice. Genes Dev. 2000 Jun 1;14(11):1343-52
1	J:255884 Laurent F, Girdziusaite A, Gamart J, Barozzi I, Osterwalder M, Akiyama JA, Lincoln J, Lopez-Rios J, Visel A, Zuniga A, Zeller R, HAND2 Target Gene Regulatory Networks Control Atrioventricular Canal and Cardiac Valve Development. Cell Rep. 2017 May 23;19(8):1602-1613
1	J:155850 Lee D, Park C, Lee H, Lugus JJ, Kim SH, Arentson E, Chung YS, Gomez G, Kyba M, Lin S, Janknecht R, Lim DS, Choi K, ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification. Cell Stem Cell. 2008 May 8;2(5):497-507
1*	J:61488 Pennisi D, Gardner J, Chambers D, Hosking B, Peters J, Muscat G, Abbott C, Koopman P, Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice. Nat Genet. 2000 Apr;24(4):434-7
1	J:118803 Ribes V, Otto DM, Dickmann L, Schmidt K, Schuhbaur B, Henderson C, Blomhoff R, Wolf CR, Tickle C, Dolle P, Rescue of cytochrome P450 oxidoreductase (Por) mouse mutants reveals functions in vasculogenesis, brain and limb patterning linked to retinoic acid homeostasis. Dev Biol. 2007 Mar 1;303(1):66-81
1*	J:50582 Roebroek AJ, Umans L, Pauli IG, Robertson EJ, van Leuven F, Van de Ven WJ , Constam DB, Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin. Development. 1998 Dec;125(24):4863-76
1	J:17509 Swiatek PJ, Lindsell CE, del Amo FF, Weinmaster G, Gridley T, Notch1 is essential for postimplantation development in mice. Genes Dev. 1994 Mar 15;8(6):707-19
1*	J:148361 Xu K, Chong DC, Rankin SA, Zorn AM, Cleaver O, Rasip1 is required for endothelial cell motility, angiogenesis and vessel formation. Dev Biol. 2009 May 15;329(2):269-79
1*	J:12605 Yamaguchi TP, Dumont DJ, Conlon RA, Breitman ML, Rossant J, flk-1, an flt-related receptor tyrosine kinase is an early marker for endothelial cell precursors. Development. 1993 Jun;118(2):489-98